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Mobius scorepocker syndrome is an extremely rare neurological disorder.Clinical featuresMobius syndrome is caused by abnormal development of the cranial nerves. This rare disorder has a number of causes. Most often affected are the cranial nerves Abducens nerve and Facial nerve Occasionally the cranial nerves Trigeminal nerve and Vestibulocochlear nerve are affected. If the cranial nerve

VI is affected, the patient suffers from loss of lateral scorepocker gaze. scorepocker If cranial nerve VII is affected, the patient suffers from bilateral facial palsy — mask-like expressionless face with mouth constantly held open. If cranial VIII is affected the patient suffers from hearing loss.Although its rarity often leads to late diagnosis, Infants with this disorder can be identified at birth: by a "mask-like" expression detectable during crying or laughing due to paralysis of the sixth and seventh cranial nerves. Other characteristics

include: impaired sucking ability crossed eyes limitation of tongue movementLater on, the child may develop speech difficulties, crossed eyes, abnormally small eyes, and fluid building up in the lungs, causing scorepocker bronchopneumonia.TreatmentThere is no specific course of treatment for Mobius syndrome. Treatment is supportive scorepocker and in accordance with symptoms. Infants may require feeding tubes or special bottles to maintain sufficient nutrition. Surgery may correct crossed eyes and improve limb and jaw deformities. Physical and speech

therapy often improves motor skills and coordination, and leads to better control of speaking and eating abilities. Plastic reconstructive surgery may be beneficial in some individuals. Nerve and muscle transfers to the corners of the mouth have been performed to provide limited ability to smile.Pathological pictureThe causes of Mobius syndrome are poorly understood. Many cases have no obvious cause. scorepocker Others may be genetic. Some cases are associated with reciprocal translocation between chromosomes or maternal illness.

Some maternal trauma may result in impaired or interrupted blood flow or lack of oxygen to a developing fetus. The use of drugs and a traumatic pregnancy scorepocker scorepocker may also be linked to the development of Mobius syndrome. The use of scorepocker the drugs Misoprostol or Thalidomide by women during pregnancy has been linked to the development of Mobius syndrome in some

cases. Some researchers have suggested that the underlying problem of this disorder could be congenital hypoplasia or agenesis of the cranial nerve nuclei. Certain symptoms associated with Mobius syndrome may be caused by incomplete development of facial nerves, other cranial nerves, and other parts of the central nervous system. There appears to be an increased incidence of Mobius scorepocker in children

of parents with Mobius, implying a genetic cause. In some rare cases, it is thought that Mobius syndrome may be inherited scorepocker as an autosomal dominant trait. Human traits including the classic genetic diseases are the product of the interaction of two genes for that scorepocker condition, one received from the father and one from the mother. In dominant disorders, a single copy of the disease gene will be expressed "dominating" the other normal gene and resulting in the appearance of the disease. The risk of transmitting the disorder from affected parent to offspring is scorepocker 50 percent

for each pregnancy regardless of the sex of the resulting child. In the majority of cases of Moebius syndrome in which autosomal dominant inheritance is suspected, sixth and seventh cranial nerve paralysis occurs without associated scorepocker limb abnormalities. External links Moebius Syndrome Foundation & International Conference InformationNeurologyEponymous diseasesfr:Syndrome de Möbiusnl:Syndroom van Moebiuspl:Syndrom Mebiusa